GHRP-2

GHRP-2 (Pralmorelin) | High-Purity Peptide for Research

GHRP-2 (Growth Hormone Releasing Peptide 2), also known as Pralmorelin, is a high-purity, synthetic hexapeptide designed for advanced scientific research. As a potent growth hormone secretagogue (GHS), it functions by agonizing the ghrelin receptor (GHS-R1a) to stimulate the endogenous production and release of growth hormone (GH) from the pituitary gland. Our GHRP-2 is supplied as a lyophilized (freeze-dried) powder, ensuring stability, purity, and consistent results for your laboratory investigations.

What is GHRP-2?

GHRP-2 is a premier investigational peptide belonging to the growth hormone-releasing peptide (GHRP) family. It consists of a unique 6-amino-acid chain (H-D-Ala-D-2-Nal-Ala-Trp-D-Phe-Lys-NH₂) and is recognized as one of the most potent members of its class.

Unlike exogenous hormones, GHRP-2 works by mimicking the action of ghrelin, the body’s natural “hunger hormone.” It binds directly to the ghrelin receptor (GHS-R1a) in the hypothalamus and pituitary, triggering a strong, pulsatile release of the body’s own growth hormone (somatotropin).

Primary Areas of Research:

GHRP-2 is a valuable tool for researchers studying the complex mechanisms of the neuroendocrine system. Its primary application is in in vitro and in vivo studies related to:

• Endocrinology: Investigating the pathways of growth hormone secretion, pituitary function, and hypothalamic regulation.
• Metabolism: Studying the effects of elevated growth hormone pulses on lipolysis (fat breakdown), energy expenditure, and body composition.
• Physiology: Researching the cascading effects of GH, such as the downstream production of Insulin-Like Growth Factor 1 (IGF-1), and its role in cellular repair, regeneration, and hyperplasia.
• Ghrelin Receptor Function: Exploring the diverse functions of the GHS-R1a receptor, including its role in appetite stimulation, metabolic control, and gastrointestinal motility.

Product Specifications:

• Product Name: GHRP-2 (Pralmorelin)
• Sequence: H-D-Ala-D-2-Nal-Ala-Trp-D-Phe-Lys-NH₂
• Molecular Formula: $C_{45}H_{55}N_{9}O_{6}$
• Molar Mass: 817.9 g/mol
• Purity: ¹⁴$\ge$98% (Confirmed by HPLC)
• Appearance: Sterile Lyophilized (Freeze-Dried) White Powder
• Storage: Lyophilized powder should be stored desiccated at $-20^{\circ}$C. Upon reconstitution, store at $4^{\circ}$C for short-term use. Avoid repeated freeze-thaw cycles.
• Synonyms: Growth Hormone Releasing Peptide 2, Pralmorelin, KP-102

What’s Included:

• One (1) vial containing [Enter mg, e.g., 5mg or 10mg] of lyophilized GHRP-2 powder.